Author

Bret Lange

Iowa State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Organism:E. coli· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Nigel Forest ReueliD· 2 shared Sepehr HejaziiD· 2 shared Basmala Aldamak· 1 shared Brandon G. Kircher· 1 shared Christopher P. JurichiD· 1 shared D. ArmstrongiD· 1 shared D. H. Sanduni DeenalatthaiD· 1 shared Joseph David YesselmaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

Nigel Forest ReuelORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-Throughput FRET Affinity Screening Technique (HTFAST) For Cell-Free Expressed Binding Protein Characterization

Sepehr Hejazi, Bret Lange, Kimia Noroozi, Vito Jurasic, Laura R. Jarboe, Nigel Forest Reuel

HTFAST enables high-throughput, quantitative affinity measurement of cell-free expressed binders using FRET, validated with nanobodies and SARS-CoV-2 sdAbs.

Small · Oct 27, 2026Peer-reviewedBioengineering

Characterizing 3D RNA structural features from DMS reactivity

D. H. Sanduni Deenalattha, Christopher P. Jurich, Bret Lange, D. Armstrong, Kaitlyn Nein, Sakshi Jain, Brandon G. Kircher, Joseph David Yesselman

The paper analyzes DMS reactivity patterns in RNA constructs to characterize 3D structural features and find correlations with hydrogen bonding and solvent accessibility.

Nucleic Acids Research · Jul 17, 2026Peer-reviewedBiochemistry

Rapid Cell-Free Combinatorial Mutagenesis Workflow Using Small Oligos Suitable for High-Iteration, Active Learning-Guided Protein Engineering

Ryan Godin, Sepehr Hejazi, Bret Lange, Basmala Aldamak, Nigel Forest Reuel

This paper introduces a cell-free combinatorial mutagenesis workflow using small oligos for high-iteration protein engineering, showing it is scalable and cost-effective.

bioRxiv · Jun 18, 2025 · PreprintBioengineering