Transient lung eosinophilia during breakthrough influenza infection in vaccinated mice is associated with protective and balanced Type 1/2 immune responses.
Lauren A. Chang, Stephen T. Yeung, Prajakta Warang, Moataz Noureddine, Gagandeep Singh, Brett T. Webb, Michael Schotsaert
This study shows that vaccinated mice experiencing breakthrough influenza infection have transient lung eosinophilia linked to balanced Type 1/2 immune responses without severe pathology.
bioRxiv · May 19, 2025 · PreprintImmunology