Gagandeep Singh

This study evaluates adjuvants for a SFTSV vaccine, finding that Addavax and SDI enhance neutralizing antibodies and immune memory, with NP as a key target.

This study shows that TIV vaccination reduces lethality in influenza-infected mice with secondary pneumococcal infections by modulating immune responses and pathogen titers.

This study identifies CLEC4E as a key driver of pro-inflammatory mDC responses in influenza using single-cell network analysis and validates its therapeutic potential in a murine model.

This study evaluates monoclonal antibody responses to XBB.1.5 vaccines by analyzing plasmablasts from vaccinated individuals and characterizing their binding and neutralization properties against SARS-CoV-2 variants.

This study shows that vaccinated mice experiencing breakthrough influenza infection have transient lung eosinophilia linked to balanced Type 1/2 immune responses without severe pathology.

The paper characterizes glycoproteins of novel fish influenza B-like viruses, revealing differences in receptor binding and antigenic conservation compared to influenza B viruses.

The paper identifies clonotype-enriched mutations in the light chain of a public antibody that enhance affinity for a conserved viral epitope and increase after repeated vaccinations.

This study identifies non-neutralizing antibodies from vaccinated individuals that protect against SARS-CoV-2 in animal models, highlighting their role through Fc-mediated effector functions and conserved epitope binding.