Age-maintained human neurons demonstrate a developmental loss of intrinsic neurite growth ability
Bo P. Lear, Elizabeth A.N. Thompson, Kendra Rodriguez, Zachary P. Arndt, Saniya Khullar, Payton C. Klosa, Ryan J. Lu, Christopher S. Morrow, Ryan D. Risgaard, Ella R. Peterson, Brian B. Teefy, Anita Bhattacharyya, André M. M. Sousa, Daifeng Wang, Bérénice Anath Benayoun, Darcie L. Moore
Directly-reprogrammed human neurons show reduced neurite growth ability with age, mirroring rodent developmental patterns.
bioRxiv · May 23, 2023 · PreprintNeuroscience