Cell BiologybioRxivPreprint
Developmental regulation of kinetochore phosphorylation determines mitotic fidelity
Brian Galaviz Sarmiento, Duane A. Compton, Kristina M. Godek
This study shows that developmental regulation of kinetochore phosphorylation, specifically HEC1 hypophosphorylation in hPSCs, leads to reduced mitotic fidelity, which is improved by differentiation.
DOI 10.64898/2026.04.15.718713