Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system
Anthony John O’Donoghue, Chenxi Lui, Carter J. Simington, Saira Montermoso, Elizabeth Moreno-Galvez, Mateus Sá Magalhães Serafim, Olive E. Burata, Rachael M. Lucero, James ThienToan Nguyen, Daniel Fong, Khanh Tran, Neomi Millan, Jamie M. Gallimore, Kamille Parungao, Jonathan Fong, , Alberto A. Rascón
This study identifies midgut proteases in Aedes aegypti mosquitoes and their role in blood meal digestion using MSP-MS, revealing shifts in proteolytic activity and substrate specificity.
PLoS neglected tropical diseases · Feb 6, 2025Peer-reviewedBiochemistry