Author

James ThienToan Nguyen

Arizona State UniversityORCID 0000-0002-9972-6252Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alberto A. RascóniD· 2 shared Daniel Fong· 2 shared Jun IsoeiD· 2 shared Mateus Sá Magalhães SerafimiD· 2 shared Olive E. BurataiD· 2 shared Rachael M. LuceroiD· 2 shared Abigail G. Ramirez· 1 shared Anthony John O’DonoghueiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiochemistry

Alberto A. RascónORCID

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2 papers

Recent·Most cited

Biochemical and physiological characterization of Aedes aegypti midgut chymotrypsin

Abigail G. Ramirez, Jun Isoe, Mateus Sá Magalhães Serafim, Daniel Fong, My Anh Le, James ThienToan Nguyen, Olive E. Burata, Rachael M. Lucero, Rebecca K. Spangler, Alberto A. Rascón

This study characterizes the activity and role of Aedes aegypti chymotrypsin in blood digestion, showing its substrate specificity and the presence of a protease network, with EcR regulating its expression.

Scientific Reports · Mar 20, 2025Peer-reviewedBiochemistry

Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system

Anthony John O’Donoghue, Chenxi Lui, Carter J. Simington, Saira Montermoso, Elizabeth Moreno-Galvez, Mateus Sá Magalhães Serafim, Olive E. Burata, Rachael M. Lucero, James ThienToan Nguyen, Daniel Fong, Khanh Tran, Neomi Millan, Jamie M. Gallimore, Kamille Parungao, Jonathan Fong, , Alberto A. Rascón

This study identifies midgut proteases in Aedes aegypti mosquitoes and their role in blood meal digestion using MSP-MS, revealing shifts in proteolytic activity and substrate specificity.

PLoS neglected tropical diseases · Feb 6, 2025Peer-reviewedBiochemistry