A RecBCD-like enzyme regulates expression of bacterial defense operons in response to DNA damage
Lydia R Chmbers, Kishen M Patel, Minheng Gong, Dwaipayan Basu, Elina Tian, Stephanie N Ouderkirk, Yaya Zhou, Qiaozhen Ye, Brian Q Pham, Tatiana V Mishanina, Aaron T. Whiteley, Kevin D Corbett
The paper identifies a bacterial pathway, Cerberus, that uses DNA damage sensing to regulate defense operon expression through anti-sigma factor cleavage.
bioRxiv · Nov 2, 2026 · PreprintBiochemistry