Decoding Cellular Stress States for Toxicology Using Single-Cell Transcriptomics
Imran Shah, David A. Gallegos, Brian Robinette, Bryant A. Chambers, Dennis J. Eastburn, Douglas A. Bell, Michelle R. Campbell, Suzanne N. Martos, Salvatore Camiolo, Kevin S. White, Nicole Martin, Gioele Montis, Joel McComb, Bruce E. Seligmann, Brian N. Chorley
The paper uses single-cell transcriptomics to analyze stress responses in HepaRG cells exposed to various chemicals, identifying distinct phenotypic groups and dynamic shifts in cellular subpopulations.
NAM journal. · Jan 1, 2025Peer-reviewedPharmacology & Toxicology