Author

Brian Yao

University of California System

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:long-read sequencing· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Gal GoldneriD· 2 shared Jennifer ListgarteniD· 2 shared Yael Michaeli· 2 shared Yuval EbensteiniD· 2 shared Assaf Grunwald· 1 shared Chloe HsuiD· 1 shared Eliran Eitan· 1 shared Jared T. SimpsoniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBioengineering

Gal GoldnerORCID

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Author profile →

2 papers

Recent·Most cited

Write and Read: Harnessing Synthetic DNA Modifications for Nanopore Sequencing

Uri Bertocchi, Assaf Grunwald, Gal Goldner, Eliran Eitan, Sigal Avraham, Shani Dvir, Jasline Deek, Yael Michaeli, Brian Yao, Jennifer Listgarten, Jared T. Simpson, Winston Timp, Yuval Ebenstein

This paper introduces a 'write-and-read' framework using synthetic DNA modifications to enable nanopore sequencing to detect chemically altered nucleotides and expand the sequence alphabet.

ACS Nano · Nov 3, 2025Peer-reviewedBioengineering

Nanopore callers for epigenetics from limited supervised data

Brian Yao, Chloe Hsu, Gal Goldner, Yael Michaeli, Yuval Ebenstein, Jennifer Listgarten

The paper demonstrates that a hybrid HMM-DNN approach outperforms both pure HMM and DNN methods for 5mC calling with incomplete training data.

bioRxiv · Jun 17, 2021 · PreprintBioinformatics