Author

Sigal Avraham

Tel Aviv University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:DNA methylation· 2 Organism:human· 2 Organism:Arabidopsis· 1 Research Focus:genome assembly· 1 Assay:long-read sequencing· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Yael Michaeli· 3 shared Yuval EbensteiniD· 3 shared Dmitry TorchinskyiD· 2 shared Elmar G. WeinholdiD· 2 shared Leonie Schütz· 2 shared Sapir Margalit· 2 shared Andreas Dankers· 1 shared Assaf Grunwald· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

Yael Michaeli

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Write and Read: Harnessing Synthetic DNA Modifications for Nanopore Sequencing

Uri Bertocchi, Assaf Grunwald, Gal Goldner, Eliran Eitan, Sigal Avraham, Shani Dvir, Jasline Deek, Yael Michaeli, Brian Yao, Jennifer Listgarten, Jared T. Simpson, Winston Timp, Yuval Ebenstein

This paper introduces a 'write-and-read' framework using synthetic DNA modifications to enable nanopore sequencing to detect chemically altered nucleotides and expand the sequence alphabet.

ACS Nano · Nov 3, 2025Peer-reviewedBioengineering

Simultaneous global labeling (SiGL) of 5-methylcytosine and 5-hydroxymethylcytosine by DNA alkylation with a synthetic cofactor and engineered methyltransferase

Sigal Avraham, Leonie Schütz, Larissa Käver, Andreas Dankers, Sapir Margalit, Yael Michaeli, Shahar Zirkin, Dmitry Torchinsky, Noa Gilat, Omer Bahr, Gil Nifker, Maya Koren‐Michowitz, Elmar G. Weinhold, Yuval Ebenstein

The paper introduces a method to simultaneously analyze 5-methylcytosine and 5-hydroxymethylcytosine in clinical samples, showing reduced 5-hydroxymethylcytosine in colorectal cancer and chronic lymphocytic leukaemia.

bioRxiv · Oct 31, 2022 · PreprintGenetics

Chemoenzymatic labeling of DNA methylation patterns for single-molecule epigenetic mapping

Tslil Gabrieli, Yael Michaeli, Sigal Avraham, Dmitry Torchinsky, Sapir Margalit, Leonie Schütz, Matyas Juhasz, Ceyda Çoruh, Nissim Arbib, Zhaohui Sunny Zhou, Julie A. Law, Elmar G. Weinhold, Yuval Ebenstein

This paper develops a chemoenzymatic method to label non-methylated CpGs in DNA, enabling single-molecule epigenetic profiling in human and plant genomes.

Nucleic Acids Research · Jun 3, 2022Peer-reviewedGenomics