Voluntary wheel running selectively preserves skeletal muscle during pancreatic cancer cachexia despite persistent systemic alterations
Cindy Richard, Arthur Dieumegard, Lou-Anne Cavrois, Luz Lefeuvre‐Orfila, Brice Martin, Laurent Rouviere, Stéphane Servais, Manuel Vlach, Gaëlle Angenard, Catherine Ribault, Anne Corlu, Pascal Loyer, Amélie Rébillard
This study compares voluntary wheel running and treadmill running in a pancreatic cancer model, finding that VWR preserves skeletal muscle while TR does not, despite similar systemic effects.
bioRxiv · Oct 20, 2026 · PreprintPhysiology