SMAD4 Mutation Drives Gut Microbiome Shifts Toward Tumor Progression in Colorectal Cancer
Travis J. Gates, Dechen Wangmo, Kyra Boorsma Bergerud, Bridget M. Keel, Christopher M. Staley, Subbaya Subramanian
This study shows that SMAD4 mutations in colorectal cancer drive microbiome changes that promote metastasis and immunosuppression.
Discover Oncology · Oct 9, 2025Peer-reviewedCancer Biology