A screen for targets of the Drosophila pseudokinase Tribbles identifies Neuralized and Mindbomb, ubiquitin ligases that mediate Notch signaling
Anna Shipman, Christopher Nauman, Britney Haymans, Rachel Silverstein, Leonard L. Dobens
The paper identifies Neuralized and Mindbomb as Tribbles targets that modulate Notch signaling by stabilizing their proteins and suppressing their activity in Drosophila.
bioRxiv · Aug 31, 2018 · PreprintDevelopmental Biology