Single-molecule live imaging of subunit interactions and exchange within cellular regulatory complexes
Thomas G.W. Graham, Claire Dugast‐Darzacq, Gina M. Dailey, Britney Weng, Sathvik Anantakrishnan, Xavier Darzacq, Robert Tjian
This study uses PAPA-fSMT to investigate P-TEFb interactions and exchange in live cells, revealing dynamics of the 7SK ribonucleoprotein complex and its association with chromatin and BRD4.
Molecular Cell · Jul 23, 2025Peer-reviewedMolecular Biology