Generation of broad-spectrum vaccine platforms against tick-borne flaviviruses using ancestral sequence reconstruction
Chasity E. Trammell, Brooke M. Enney, Michelle J. Savran, Brian J. Geiss, Gregory D. Ebel
This study uses ancestral sequence reconstruction to design a vaccine platform against multiple tick-borne flaviviruses, showing broad protection in mice.
bioRxiv · Oct 31, 2025 · PreprintMicrobiology