Repressive gene regulation synchronizes development with cellular metabolism
Justin J. Cassidy, Sebastian M. Bernasek, Rachael A. Bakker, Ritika Giri, Nicolás Peláez, Bryan Eder, Anna Bobrowska, Neda Bagheri, Luı́s A. Nunes Amaral, Richard W. Carthew
The paper shows that layered weak repression synchronizes developmental gene regulation with cellular metabolism, and that reducing metabolism can compensate for loss of repressors.
Cell · Jul 25, 2019Peer-reviewedDevelopmental Biology