Author

Bryant Harbourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Arun M. Unni· 1 shared Harold Varmus· 1 shared Min Hee Oh· 1 shared Sophia Wild· 1 shared William W. Lockwood· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

Arun M. Unni

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1 paper

Recent·Most cited

Hyperactivation of extracellular signal-regulated kinase (ERK) by RAS-mediated signaling or inhibition of dual specificity phosphatase 6 (DUSP6) is associated with toxicity in lung adenocarcinoma cells with mutations in KRAS or EGFR

Arun M. Unni, Bryant Harbourne, Min Hee Oh, Sophia Wild, William W. Lockwood, Harold Varmus

The paper identifies ERK hyperactivation via RAS signaling or DUSP6 inhibition as toxic in KRAS or EGFR mutant lung adenocarcinoma cells, suggesting therapeutic strategies targeting feedback regulators.

bioRxiv · Nov 21, 2017 · PreprintCancer Biology