Bazedoxifene rescues sexually dimorphic autistic-like abnormalities in mice carrying a biallelic MDGA1 mutation
Seungjoon Kim, Jinhu Kim, Byeong Chan Kim, Hyeonho Kim, Yeji Yang, Hea Ji Lee, Jin Young Kim, Ji Won Um, Jaewon Ko
This study shows that bazedoxifene treatment rescues ASD-like behaviors in male mice with a specific MDGA1 mutation, but not in females.
bioRxiv · Jun 1, 2025 · PreprintNeuroscience