Wnt and Nodal asymmetries stratify mouse laterality phenotypes in the absence of node flow
Amaia Ochandorena-Saa, Émeline Perthame, Zoé Oulerich, Alexander Chamolly, Thierry Blisnick, Johanna Lokmer, Cécile Rouillon, Philippe Bastin, Sigolène M. Meilhac
The paper shows that Wnt and Nodal asymmetries contribute to left-right asymmetry in mice despite the absence of node flow, suggesting a novel mechanism for symmetry breaking.
Science Advances · Jul 23, 2026Peer-reviewedDevelopmental Biology