miR-181a Regulates p62/SQSTM1, Parkin and Protein DJ-1 Promoting Mitochondrial Dynamics in Skeletal Muscle Ageing
K. Goljanek-Whysall, A. Soriano-Arroquia, R. McCormick, C. A. Chinda, B. McDonagh
This study shows miR-181a regulates mitochondrial dynamics in skeletal muscle ageing by controlling p62/SQSTM1, Parkin, and DJ-1, and restoring miR-181a improves mitochondrial quality and muscle function in aged mice.
bioRxiv · Oct 16, 2019Physiology