K. Goljanek-Whysall

This study examines how maternal low protein diet during lactation affects skeletal muscle development and ageing in male and female mouse offspring, finding sexual dimorphism in outcomes.

This study shows that low maternal and postnatal protein diets in mice affect skeletal muscle structure and function, while postnatal low protein diet increases bone mass.

This study shows that MHC I overexpression in muscle cells induces ER stress, leading to pro-inflammatory cytokine release, which is reduced by salubrinal.

This study shows miR-24-3p and its target Prdx6 regulate oxidative stress and viability of myogenic progenitors during ageing, with miR-24 downregulation in old mice linked to increased ROS and satellite cell senescence.

This study shows that low protein intake during lactation impairs bone recovery in female mice but not skeletal muscles, with partial recovery when diet is normalized post-weaning.

This study shows miR-181a regulates mitochondrial dynamics in skeletal muscle ageing by controlling p62/SQSTM1, Parkin, and DJ-1, and restoring miR-181a improves mitochondrial quality and muscle function in aged mice.