Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation
A. Peixoto, R. A. Freitas, D. A. Ferreira, M. Relvas-Santos, P. Paulo, M. Cardoso, J. Soares, C. A. Gaiteiro, C. Palmeira, F. Teixeira, R. Ferreira, M. J. Oliveira, A. Silva, L. L. Santos, J. A. Ferreira
This study shows that bladder cancer cells become more aggressive under hypoxia and glucose deprivation through metabolic and glycosylation changes.
bioRxiv · Feb 14, 2021 · PreprintCancer Biology