Bromodomains regulate dynamic targeting of the PBAF chromatin remodeling complex to chromatin hubs
C. A. Kenworthy, N. Haque, S.-H. Liou, P. Chandris, V. Wong, P. Dziuba, L. D. Lavis, W.-L. Liu, R. H. Singer, R. A. Coleman
This study uses live-cell imaging to show that PBAF chromatin remodeler dynamically targets acetylated chromatin hubs via bromodomains, with distinct binding kinetics in euchromatin and heterochromatin.
bioRxiv · Nov 2, 2021Cell Biology