A Predictive Model of Intercellular Tension and Cell-Matrix Mechanical Interactions in a Multicellular Geometry
L. E. Scott, L. A. Griggs, V. Narayanan, D. E. Conway, C. A. Lemmon, S. H. Weinberg
The paper develops a multicellular computational model to simulate intercellular tension and cell-matrix interactions during epithelial-mesenchymal transition, showing it can reproduce key aspects of EMT dynamics and spatial patterning.
bioRxiv · Jul 12, 2019Cell Biology