S. H. Weinberg

Unraveling Chamber-specific Differences in Intercalated Disc Ultrastructure and Molecular Organization and Their Impact on Cardiac Conduction

This study quantifies intercalated disc structure in mouse heart chambers using advanced imaging and modeling to reveal chamber-specific differences in conduction speed.

Sodium channel subpopulations with distinct biophysical properties and subcellular localization enhance cardiac conduction

This study uses computational models to show that distinct sodium channel subpopulations with different biophysical properties and locations affect cardiac conduction speed and robustness.

Emergent Electrical Activity, Tissue Heterogeneity, and Robustness in a Calcium Feedback Regulatory Model of the Sinoatrial Node

Effects of substrate stiffness and actin velocity on fibronectin fibril morphometry and mechanics

This study uses a computational model to investigate how cell contractility and tissue stiffness influence fibronectin fibril formation and mechanics.

A Predictive Model of Intercellular Tension and Cell-Matrix Mechanical Interactions in a Multicellular Geometry

The paper develops a multicellular computational model to simulate intercellular tension and cell-matrix interactions during epithelial-mesenchymal transition, showing it can reproduce key aspects of EMT dynamics and spatial patterning.

Cell fate forecasting: a data assimilation approach to predict epithelial-mesenchymal transition

This paper demonstrates a data assimilation approach using an ensemble Kalman filter to predict epithelial-mesenchymal transition (EMT) state transitions by integrating noisy observations with a computational model of TGFβ-induced EMT.

Mechanochemical coupling and junctional forces during collective cell migration

This study models mechanochemical interactions and junctional forces in collective cell migration, showing biphasic feedback between mechanical tension and Rho GTPase activity, and how junctional forces influence migration speed and tissue size.