Author

C. A. R. Cotton

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Biochemistry· 2

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Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Aspuru-Guzik· 1 shared A. Bar-Even· 1 shared A. Flamholz· 1 shared A. Jinich· 1 shared B. Sanchez-Lengeling· 1 shared B. V. Kabasakal· 1 shared E. Noor· 1 shared H. Ren· 1 shared

Activity by Year

2018-2023 · peak 1/yr

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10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Aspuru-Guzik

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMar 21, 2023

Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA Reductase controls the reaction

B. V. Kabasakal, C. A. R. Cotton, J. W. Murray

The paper presents crystal structures of the N-terminal and C-terminal regions of MCR from C. aurantiacus, revealing a lid domain that undergoes conformational changes to control the reaction mechanism.

DOI 10.1101/2023.03.21.533589

C. elegansstructural biology

𝕏 PostBluesky

BiochemistrybioRxivJan 9, 2018

Quantum chemistry reveals the thermodynamic principles of redoxbiochemistry

A. Jinich, A. Flamholz, H. Ren…·A. Bar-Even

This study uses quantum chemistry to calculate redox potentials of biochemical reactions, revealing thermodynamic trends and explaining the role of NAD/NADP in cellular metabolism.

DOI 10.1371/journal.pcbi.1006471

deep learningchromatin & epigenetic regulation

𝕏 PostBluesky