Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma
M. L. Orozco Morales, C. A. Rinaldi, E. de Jong, S. M. Lansley, Y. C. G. Lee, R. M. Zemek, A. Bosco, R. A. Lake, W. J. Lesterhuis
The paper evaluates geldanamycin's anti-cancer effects in mesothelioma models, finding it inhibits tumor cells in vitro but not in vivo.
bioRxiv · Aug 29, 2022Cancer Biology