BioengineeringbioRxiv
Transcriptome profiling of human pluripotent stem cell-derived cerebellar organoids reveals fastercommitment under dynamic conditions
T. P. Silva, R. Sousa-Luis, T. G. Fernandes…·J. M. S. Cabral
This study shows that dynamic differentiation using Vertical-Wheel bioreactors produces cerebellar organoids with faster commitment and enriched extracellular matrix, improving their neural microenvironment and functional maturation.
DOI 10.1002/bit.27797