Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in Black American and White American patients with TNBC
Q. Zhu, A. Balasubramanian, J. R. Asirvatham, M. Chatterjee, D. W. B. Piyarathna, J. Kaur, N. Mohamed, L. Wu, S. Wang, N. Pourfarrokh, P. D. Binsol, M. Bhargava, U. Rasaily, Y. Xu, J. Zheng, , A. Sreekumar
This study uses spatial omics to identify distinct tumor microenvironment profiles in Black and White American TNBC patients, linking them to different immunosuppressive mechanisms and clinical outcomes.
bioRxiv · Mar 17, 2024Cancer Biology