Author

C. B. Lessard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

D. M. Holtzman· 1 shared J. D. Ulrich· 1 shared M. Colonna· 1 shared P. Chakrabaty· 1 shared P. E. Cruz· 1 shared S. L. Malnik· 1 shared T. B. Ladd· 1 shared T. E. Mahan· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

D. M. Holtzman

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1 paper

Recent·Most cited

High affinity interactions and signal transduction between Aβ oligomers and TREM2

C. B. Lessard, S. L. Malnik, Y. Zhou, T. B. Ladd, P. E. Cruz, Y. Ran, P. Chakrabaty, T. E. Mahan, D. M. Holtzman, J. D. Ulrich, M. Colonna, T. Golde

This study investigates the high-affinity interaction between TREM2 and Aβ oligomers, showing that AD-associated TREM2 variants have reduced signaling and internalization capacity.

bioRxiv · Feb 22, 2018Cell Biology