Battle for the histones: a secreted bacterial sirtuin from Campylobacter jejuni activates neutrophils and induces inflammation during infection
S. M. Callahan, T. J. Hancock, R. S. Doster, C. B. Parker, M. E. Wakim, J. A. Gaddy, J. G. Johnson
This study identifies a secreted bacterial sirtuin, SliP, from Campylobacter jejuni that deacetylates host histones, activates neutrophils, and drives inflammation during infection.
bioRxiv · Jul 19, 2022 · PreprintMicrobiology