Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
M. E. Pell, H. M. Blankenship, J. A. Gaddy, H. D. Davies, S. D. Manning
This study identifies genomic adaptations in group B Streptococcus (GBS) following intrapartum antibiotic prophylaxis, showing increased mutation rates and biofilm production in persistent colonizers.
bioRxiv · Apr 1, 2024Evolutionary Biology
A. Crabtree, K. Neikirk, J. Pinette, A. Whiteside, B. Shao, J. McKenzie, Z. Vue, L. Vang, H. Le, M. Demirci, T. Ahmad, T. C. Owens, A. Oliver, F. Zeleke, H. K. Beasley, , A. Hinton
This study quantifies age-related changes in lipid droplet morphology and mitochondria-lipid interactions in murine brown adipose tissue using 3D imaging and analysis.
bioRxiv · Sep 23, 2023Biophysics
D. C. Stephens, M. Mungai, A. Crabtree, H. K. Beasley, E. Garza-Lopez, L. Vang, K. Neikirk, Z. Vue, N. Vue, A. G. Marshall, K. Turner, J.-q. Shao, B. Sarker, S. A. Murray, J. A. Gaddy, , A. Hinton
The paper describes a method to isolate skeletal muscle from mice, generate satellite cells for culture, and validate cell populations using immunofluorescence.
bioRxiv · May 20, 2023Cell Biology
D. C. Stephens, A. Crabtree, H. K. Beasley, E. Garza-Lopez, K. Neikirk, M. Mungai, L. Vang, Z. Vue, N. Vue, A. G. Marshall, K. Turner, J.-q. Shao, S. A. Murray, J. A. Gaddy, C. Wanjalla, , A. Hinton
This paper describes a protocol for using proximity ligation assays (PLA) to study protein-protein interactions in mitochondria-endoplasmic reticulum contact sites (MERCs) in mouse skeletal muscle tissue and cells.
bioRxiv · May 20, 2023Cell Biology
D. C. Stephens, A. Crabtree, H. K. Beasley, E. Garza-Lopez, M. Mungai, K. Neikirk, L. Vang, Z. Vue, N. Vue, A. G. Marshall, K. Turner, J.-q. Shao, S. A. Murray, J. A. Gaddy, C. Wanjalla, , A. Hinton
This paper presents an optimized western blot protocol to isolate and detect five OPA1 isoforms in muscle tissue.
bioRxiv · May 20, 2023Cell Biology
B. Shao, M. Killion, A. Oliver, C. Vang, F. Zeleke, K. Neikirk, Z. Vue, E. Garza-Lopez, J.-q. Shao, M. Mungai, J. Lam, Q. Williams, C. Altamura, A. Whiteside, K. Kabugi, , A. Hinton
This study shows that Sam50 deficiency in myotubes leads to mitochondrial fragmentation, altered metabolism, and impaired oxidative capacity in both mice and humans.
bioRxiv · May 20, 2023Physiology
S. M. Callahan, T. J. Hancock, R. S. Doster, C. B. Parker, M. E. Wakim, J. A. Gaddy, J. G. Johnson
This study identifies a secreted bacterial sirtuin, SliP, from Campylobacter jejuni that deacetylates host histones, activates neutrophils, and drives inflammation during infection.
bioRxiv · Jul 19, 2022 · PreprintMicrobiology
Z. Vue, K. Neikirk, L. Vang, E. Garza-Lopez, T. A. Christensen, J.-q. Shao, J. Lam, H. K. Beasley, A. G. Marshall, A. Crabtree, J. Anudokem, B. Rodriguez, B. Kirk, S. Bacevac, T. Barongan, , A. Hinton
This study uses 3D imaging to show that mitochondria in aging mouse hearts lose cristae structure and volume, similar to mutations in MICOS complex genes.
bioRxiv · Apr 23, 2022Biophysics
Z. Vue, E. Garza-Lopez, K. Neikirk, P. Katti, L. Vang, H. K. Beasley, J.-q. Shao, A. G. Marshall, A. Crabtree, A. C. Murphy, B. C. Jenkins, P. Prasad, C. S. Evans, B. T. Taylor, M. Mungai, , Murray
This study examines age-related changes in mitochondrial 3D structure in mouse muscle and heart tissues, linking these changes to the MICOS complex and metabolic alterations.
bioRxiv · Mar 22, 2022Biophysics
E. Skoog, V. A. Morikis, M. E. Martin, G. A. Foster, L. P. Cai, L. M. Hansen, B. Li, J. A. Gaddy, S. Simon, J. V. Solnick
This study shows that recombination in the CagY MRR of H. pylori modulates T4SS function by altering binding to 5β1 integrin, which affects host inflammatory responses and bacterial colonization.
bioRxiv · Apr 4, 2018Microbiology