Author

C. Blenkiron

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. L. Hisey· 3 shared L. W. Chamley· 3 shared A. Artuyants· 2 shared A. Bartlett· 1 shared A. Lim· 1 shared A. MacCormick· 1 shared A. Tyler· 1 shared B. Jacob· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

C. L. Hisey

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Manifold Learning Enables Interpretable Analysis of Raman Spectra from Extracellular Vesicle and Other Mixtures

M. Kazemzadeh, M. Martinez-Calderon, R. Otupiri, A. Artuyants, M. Lowe, X. Ning, E. Reategui, Z. D. Schultz, W. Xu, C. Blenkiron, L. W. Chamley, N. G. R. Broderick, C. L. Hisey

This paper uses manifold learning on Raman spectra to quantify EV mixtures and demonstrate its applicability to other Raman spectroscopy applications.

bioRxiv · Mar 20, 2023 · PreprintBioengineering

Investigating the Consistency of Extracellular Vesicle Production from Breast Cancer Subtypes Using CELLine Adherent Bioreactors

C. L. Hisey, A. Artuyants, G. Guo, V. Chang, G. Reshef, M. Middleditch, B. Jacob, L. W. Chamley, C. Blenkiron

This study shows that CELLine AD 1000 bioreactors can consistently produce EVs from multiple breast cancer subtypes, with stable core protein content over time.

Journal of Extracellular Biology · Sep 22, 2022Peer-reviewedCancer Biology

Automated Parallel Pattern Search Optimisation of Microfluidic Geometry for Extracellular Vesicle Liquid Biopsies

C. L. Hisey, A. Tyler, A. Lim, L. W. Chamley, C. Blenkiron, R. J. Clarke

The paper optimizes microfluidic geometry for extracellular vesicle capture using automated parallel pattern search, finding that larger pillars with spacing improve capture efficiency.

bioRxiv · Nov 13, 2021 · PreprintBioengineering

Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer

B. Lawrence, C. Blenkiron, K. Parker, P. Tsai, S. Fitzgerald, P. Shields, M. L. Yeong, N. Kramer, T. Robb, S. M. James, M. Black, V. Fan, N. Poonawala, P. Yap, E. Coats, , C. G. Print

The paper identifies two distinct aneuploidy patterns in pancreatic neuroendocrine tumors (pNETs) associated with poor and good clinical outcomes, respectively, and highlights MEN1 mutations as a significant driver.

bioRxiv · Nov 8, 2017Cancer Biology