Author

B. Lawrence

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

H. Levis· 3 shared R. D. Bowles· 3 shared C. Lewis· 2 shared J. D. Weston· 2 shared A. Bartlett· 1 shared A. Lawal· 1 shared A. MacCormick· 1 shared B. Austin· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBioengineering

H. Levis

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ZNF865 Regulates Senescence and Cell Cycle for Applications to Cell Engineering and Gene Therapy

H. Levis, C. Lewis, E. Stockham, J. D. Weston, A. Lawal, B. Lawrence, S. E. Gullbrand, R. D. Bowles

This study identifies ZNF865 as a regulator of senescence and cell cycle, demonstrating its potential for cell engineering and gene therapy applications.

bioRxiv · Oct 25, 2023Bioengineering

Therapeutic TNF-alpha Delivery After CRISPR Receptor Modulation in the Intervertebral Disc

J. D. Stover, M. A. R. Trone, J. Weston, C. Lewis, H. Levis, M. Philippi, M. Zeidan, B. Lawrence, R. D. Bowles

This study uses CRISPR to modulate TNFR1 in rats, reducing disc degeneration and showing that TNF-alpha injection becomes therapeutic after receptor modulation.

bioRxiv · May 31, 2023Bioengineering

CRISPRi-Driven Osteogenesis in Adipose-Derived Stem Cells for Bone Healing and Tissue Engineering

J. D. Weston, B. Austin, H. Levis, J. Zitnay, J. A. Weiss, B. Lawrence, R. D. Bowles

This study uses CRISPRi to downregulate BMP antagonists in adipose-derived stem cells, promoting osteogenesis without exogenous growth factors and demonstrating multiplex tissue engineering applications.

bioRxiv · Nov 15, 2022Bioengineering

SSNA1 stabilizes dynamic microtubules and detects microtubule damage

B. Lawrence, C. Arnaiz, G. Arpag, M. Zanic

This study investigates SSNA1's effects on microtubules, finding it stabilizes dynamic microtubules and detects damage.

bioRxiv · Feb 5, 2021Biophysics

Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer

B. Lawrence, C. Blenkiron, K. Parker, P. Tsai, S. Fitzgerald, P. Shields, M. L. Yeong, N. Kramer, T. Robb, S. M. James, M. Black, V. Fan, N. Poonawala, P. Yap, E. Coats, , C. G. Print

The paper identifies two distinct aneuploidy patterns in pancreatic neuroendocrine tumors (pNETs) associated with poor and good clinical outcomes, respectively, and highlights MEN1 mutations as a significant driver.

bioRxiv · Nov 8, 2017Cancer Biology