Elimination of Foxo triplets following glucocorticoid incubation dampened metabolic stress and enhanced anti-viral response targets based on transcriptomic analysis
P. Puthanveetil, D. Rafferty, B. Gan, C. Bolch
The paper shows that deleting Foxo triplets in mouse cells reduces metabolic stress and enhances anti-viral response while maintaining anti-inflammatory effects of glucocorticoids.
bioRxiv · Nov 17, 2022 · PreprintPharmacology & Toxicology