cDC1 and interferons promote spontaneous CD4+ and CD8+ T cell protective responses to breast cancer
R. Mattiuz, C. Brousse, M. Ambrosini, J.-C. Cancel, G. Bessou, J. Mussard, A. Sanlaville, C. Caux, N. Bendriss-Vermare, J. Valladeau-Guilemond, M. Dalod, K. Crozat
This study shows that cDC1 and interferons are critical for CD4+ and CD8+ T cell responses against breast cancer, promoting infiltration and effector functions, and improving patient prognosis.
bioRxiv · Dec 23, 2020Immunology