GIGYF2 mediates post-transcriptional mRNA repression through recruitment of the CCR4/NOT complex
C. C. Amaya Ramirez, P. Hubbe, N. Mandel, J. Bethune
This study identifies two distinct mechanisms by which GIGYF2 mediates mRNA repression: one through m4EHP-dependent translation repression and another through CCR4/NOT complex-mediated deadenylation.
bioRxiv · Sep 3, 2017Biochemistry