Author

P. Hubbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:structural biology· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

C. C. Amaya Ramirez· 1 shared J. Bethune· 1 shared J. Kopp· 1 shared J. L. Gerber· 1 shared J. Peschek· 1 shared L. Worf· 1 shared N. Mandel· 1 shared S. I. M. Guzman· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

C. C. Amaya Ramirez

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Author profile →

2 papers

Recent·Most cited

Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease

J. L. Gerber, S. I. M. Guzman, L. Worf, P. Hubbe, J. Kopp, J. Peschek

The paper reports structural and biochemical analysis of the human RTCB-Archease complex during RNA ligation, revealing the mechanism of GTP-dependent activation and substrate regulation.

bioRxiv · Mar 30, 2023Biochemistry

GIGYF2 mediates post-transcriptional mRNA repression through recruitment of the CCR4/NOT complex

C. C. Amaya Ramirez, P. Hubbe, N. Mandel, J. Bethune

This study identifies two distinct mechanisms by which GIGYF2 mediates mRNA repression: one through m4EHP-dependent translation repression and another through CCR4/NOT complex-mediated deadenylation.

bioRxiv · Sep 3, 2017Biochemistry