Functional cardiac consequences of β-adrenergic stress-induced injury in the mdx mouse model of Duchenne muscular dystrophy
C. C. Earl, A. J. Javier, A. M. Richards, L. W. Markham, C. J. Goergen, S. S. Welc
This paper introduces a method using low-dose isoproterenol to enhance cardiac dysfunction in mdx mice, showing increased myocyte injury, fibrosis, and reduced ventricular function compared to wild-type mice.
bioRxiv · Apr 15, 2024 · PreprintPhysiology