Author

R. D. Huff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

J. A. Hirota· 2 shared M. D. Inman· 2 shared N. Tiessen· 2 shared A. C. Doxey· 1 shared C. C. Earl· 1 shared C. Cao· 1 shared C. Harris-Adamson· 1 shared C. J. Goergen· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

J. A. Hirota

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deep learning enables accurate soft tissue deformation estimation in vivo

R. D. Huff, F. Houghton, C. C. Earl, E. Ghajar-Rahimi, I. Dogra, D. Yu, C. Harris-Adamson, C. J. Goergen, G. D. O'Connell

This paper introduces StrainNet, a deep learning model that accurately estimates in vivo tissue deformation, outperforming traditional methods by nearly 90%.

bioRxiv · Sep 4, 2023 · PreprintBioengineering

Potentiation of Long-Acting β2-Agonist and Glucocorticoid Responses in Human Airway Epithelial Cells by Modulation of Intracellular cAMP

Y. Kim, V. Hou, R. D. Huff, J. A. Aguiar, S. Revill, N. Tiessen, C. Cao, M. S. Miller, M. D. Inman, K. Ask, A. C. Doxey, J. A. Hirota

This study shows that inhibiting PDE4 or ABCC4 enhances the anti-inflammatory effects of LABA/GCS in human airway epithelial cells exposed to viral stimuli.

bioRxiv · Nov 9, 2020Immunology

Modulation of cAMP metabolism for CFTR potentiation in human airway epithelial cells

J. P. Nguyen, M. Bianca, R. D. Huff, N. Tiessen, M. D. Inman, J. A. Hirota

This study tests cAMP modulation via ABCC4 and PDE-4 inhibition as an add-on therapy to VX-770 to increase CFTR activity in human airway epithelial cells.

bioRxiv · Sep 11, 2020Cell Biology