Author

C. C. Ence

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Microbiology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. K. Chatterjee· 1 shared A. Sharma· 1 shared B. Melillo· 1 shared E. Comer· 1 shared H. Xie· 1 shared J. Borrel· 1 shared J. Zoller· 1 shared L. D. Sibley· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

A. K. Chatterjee

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1 paper

Recent·Most cited

Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure

C. C. Ence, T. Uddin, J. Borrel, P. Mittal, H. Xie, J. Zoller, A. Sharma, E. Comer, S. L. Schreiber, B. Melillo, L. D. Sibley, A. K. Chatterjee

This paper describes new bicyclic pyrrolidine inhibitors of Toxoplasma gondii PheRS with improved potency, selectivity, and brain exposure compared to previous azetidine-based inhibitors.

bioRxiv · Feb 28, 2024 · PreprintMicrobiology