A redox-dependent mechanism for AMPK dysregulation interrupts metabolic adaptation of cancer under glucose deprivation
Y. Lee, Y. Itahana, C. C. Ong, K. Itahana
This study identifies a redox-dependent mechanism by which AMPK dysregulation leads to metabolic failure in glucose-deprived cancer cells, specifically in xCT-high expressing lines.
bioRxiv · Mar 10, 2021 · PreprintCancer Biology