GRAMD1C promotes autophagy initiation and mitochondrial bioenergetics through regulation of ER-mitochondria cholesterol transport
M. Y. W. Ng, C. Charsou, A. S. D. S. Lapao, S. Singh, L. Trachsel-Moncho, S. Nakken, M. J. Munson, A. Simonsen
This study identifies GRAMD1C as a negative regulator of starvation-induced autophagy and mitochondrial function through cholesterol transport between the ER and mitochondria.
bioRxiv · Aug 4, 2021 · PreprintBiochemistry