Kinetic And Structural Parameters Governing Fic-Mediated Adenylylation/AMPylation of the Hsp70 chaperone, BiP/GRP78
S. Mattoo, A. Sanyal, E. A. Zbornik, B. G. Watson, C. Christoffer, J. Ma, D. Kihara
This study investigates the kinetic and structural parameters of HYPE-mediated adenylylation/AMPylation of BiP/GRP78, revealing site-specific effects on ATPase activity and substrate recognition.
bioRxiv · Dec 13, 2018Biochemistry