β-HPV 8E6 Dysregulates the Hippo Signaling Pathway and Induces Aneuploidy
D. Dacus, T. X. McCallister, C. Cotton, E. Rigiofoirate, N. A. Wallace
This paper shows that β-HPV 8E6 disrupts the Hippo signaling pathway, leading to increased cell growth and aneuploidy, and synergizes with telomerase activation to promote genomic instability.
bioRxiv · Sep 6, 2019 · PreprintCancer Biology