RAS mutation patterns arise from tissue-specific responses to distinct oncogenic signaling
O. Erdogan, N. L. K. Pershing, E. Kaltenbrun, N. J. Newman, J. Everitt, C. Counter
This study shows how different KRAS mutations drive distinct transcriptional responses in normal cells, leading to tissue-specific cancer types.
bioRxiv · Dec 10, 2021Cancer Biology