Author

C. Craik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:plant (other)· 1

Frequent Co-Authors

F. Caiazza· 2 shared A. C. Margets· 1 shared A. S. Chicowski· 1 shared A. Sali· 1 shared B. Nolan· 1 shared C. Montes-Serey· 1 shared D. Fennelly· 1 shared D. Kroetz· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPlant Biology

F. Caiazza

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A soybean rust effector protease suppresses host immunity and cleaves a 3-deoxy-7-phosphoheptulonate synthase

A. S. Chicowski, M. Qi, H. Variz, M. Bredow, C. Montes-Serey, F. Caiazza, H. Dong, A. C. Margets, J. Mejias, J. Walley, C. Craik, K. F. Pedley, K. Aung, R. W. Innes, S. Whitham

This study identifies PpEC15, a soybean rust effector protease, which suppresses host immunity by cleaving a 3-deoxy-7-phosphoheptulonate synthase and modulating immune signaling pathways.

bioRxiv · Sep 7, 2023 · PreprintPlant Biology

Structural Basis of Prostaglandin Efflux by MRP4

S. Pourmal, E. Green, R. Bajaj, I. Chemmama, G. Knudsen, M. Gupta, A. Sali, Y. Cheng, C. Craik, D. Kroetz, R. Stroud

This study determines the cryo-EM structures of MRP4 bound to prostaglandins and DHEA-S, revealing its unique substrate specificity and transport mechanism.

bioRxiv · Dec 22, 2022Biochemistry

KH-type splicing regulatory protein controls colorectal cancer cell growth and modulates the tumor microenvironment

F. Caiazza, K. Oficjalska, M. Tosetto, J. Phelan, S. Noonan, P. Martin, K. Killick, L. Breen, F. O'Neill, B. Nolan, S. Furney, R. Power, D. Fennelly, C. Craik, J. O'Sullivan, , E. Ryan

This study investigates KHSRP's role in colorectal cancer, showing it promotes tumor growth and modulates the tumor microenvironment through mechanisms involving cell proliferation and angiogenesis.

The American Journal of Pathology · Oct 1, 2019Peer-reviewedCancer Biology