Author

J. Phelan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:whole-genome sequencing· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. A. van Belkum· 1 shared A. Bagaev· 1 shared A. Coello Pelegrin· 1 shared A. J. Radtke· 1 shared A. L. Shaffer· 1 shared A. Varlamova· 1 shared B. C. Lowekamp· 1 shared B. Nolan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. A. van Belkum

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The polyamines spermine and spermidine inhibit or induce programmed cell death in Arabidopsis thaliana in vitro and in vivo in a dose dependent manner.

R. Burke, D. Nicotra, J. Phelan, P. F. McCabe, J. Kacprzyk

This study shows that spermine and spermidine regulate programmed cell death in Arabidopsis in a dose-dependent manner, acting as either inhibitors or inducers.

bioRxiv · Nov 15, 2023 · PreprintPlant Biology

A Multi-scale, Multiomic Atlas of Human Normal and Follicular Lymphoma Lymph Nodes

A. J. Radtke, E. Postovalova, A. Varlamova, A. Bagaev, M. Sorokina, O. Kudryashova, M. Meerson, M. Polyakova, I. Galkin, V. Svekolkin, S. Isaev, G. Perelman, Y. Lozinsky, Z. Yaniv, B. C. Lowekamp, , R. N. Germain

This study creates a multi-scale, multiomic atlas of human normal and follicular lymphoma lymph nodes to identify tumor-specific features and microenvironmental patterns associated with early relapse.

bioRxiv · Jun 3, 2022Cancer Biology

Recombinant Origin and Interspecies Transmission of a HERV-K(HML-2)-related Primate Retrovirus 1 With a Novel RNA Transport Element

Z. H. Williams, L. Gaucherand, D. C. Lee, S. M. Mostafa, J. Phelan, J. M. Coffin, W. E. Johnson

The paper identifies recent HML-2 provirus activity in rhesus macaques and shows interspecies transmission to gibbons, with a novel RNA transport element replacing the ancestral Rec-RcRE system.

bioRxiv · May 11, 2022Microbiology

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: An inter-laboratory study

R. M. Doyle, D. M. O'Sullivan, S. D. Aller, S. Bruchmann, T. G. Clark, A. Coello Pelegrin, M. Cormican, E. Diez Benavente, M. J. Ellington, E. McGrath, Y. Motro, T. Phuong Thuy Nguyen, J. Phelan, L. P. Shaw, R. A. Stabler, , K. A. Harris

This study evaluates the reproducibility of antimicrobial resistance predictions from whole-genome sequencing data across different laboratories and identifies factors contributing to discordant results.

Microbial Genomics · Feb 1, 2020Peer-reviewedMicrobiology

KH-type splicing regulatory protein controls colorectal cancer cell growth and modulates the tumor microenvironment

F. Caiazza, K. Oficjalska, M. Tosetto, J. Phelan, S. Noonan, P. Martin, K. Killick, L. Breen, F. O'Neill, B. Nolan, S. Furney, R. Power, D. Fennelly, C. Craik, J. O'Sullivan, , E. Ryan

This study investigates KHSRP's role in colorectal cancer, showing it promotes tumor growth and modulates the tumor microenvironment through mechanisms involving cell proliferation and angiogenesis.

The American Journal of Pathology · Oct 1, 2019Peer-reviewedCancer Biology