Modeling site-specific nucleotide biases affecting Himar1 transposon insertion frequencies in TnSeq datasets
S. Choudhery, A. J. Brown, C. D. Akusobi, E. J. Rubin, C. M. Sassetti, T. R. Ioerger
This paper identifies site-specific nucleotide biases affecting Himar1 transposon insertion frequencies in TnSeq datasets and introduces a new method to improve the identification of conditionally essential genes.
bioRxiv · Jul 1, 2021Microbiology